Dentistry

Oral Biology1

Biologia Oral

Course code:9548205

Ana Cristina Garcia de Matos Manso

Learning outcomes of the curricular unit:

To transform and integrate pre-acquired basic knowledge regarding oral biochemistry and molecular biology into the undergraduate curriculum. To apply this knowledge in relationship to homeostasis of the oral cavity, awakening in the student the notion that there are plausible biological risk factors that can be understood and prevented in the biological-dynamic of positive health. The student should be competent to: a) have knowledge about the structural and functional organization of the hard and soft tissues of the oral cavity in health conditions, in OB; b) integrate and apply the knowledge of OB, in experimental situations and / or in correlation with its future application, in the field of dentistry; c) understand and apply the syllabus in the stomatognathic system, as an integral part of the organism and the integral health of the individual.

Syllabus:
  • The dental organ and its periodontal support.
  • Oral junctional epithelium - How important is it? Free gum, Gum inserted, Gingival sulcus.
  • Connective tissue and extracellular matrix - crucial insight into your knowledge and study. Collagen, elastin, glycoproteins, proteoglycans and glycosaminoglycans.
  • Inflammation and infection.
  • Dental wear - chemical, mechanical and erosive.
  • Fluoride: What is fluorine? How does it protect us from dental caries? Dental fluorosis.
  • Sugar, dental biofilm, environmental acidification and dental caries.
  • Biological mineralization of bone, enamel and dentin - Defects in enamel and dentin.
  • Brief description of what biologically represents “tooth movement”.
  • What are metalloproteases? How important is its role in the breakdown of collagen, stromal tissue and enamel synthesis?
  • Salivary glands and saliva.
Suggested Bibliography:
  • Cole AS, Eastoe JE (1988) Biochemistry and Oral Biology. 4th ed., Wright and Sons. ISBN- 0723608342.
  • Kantarci A, Will L, Yen S (2016) Tooth Movement. Karger, Amsterdan. ISBN: 978-3-318-05479-8. e-ISBN: 978-3-318-05480-4.
  • Levine M (2011) Topics in Dental Biochemistry. Springer-Verlag Berlin Heidelberg. ISBN 978-3-540-88115-5. e-ISBN 978-3-540-88116-2
  • Ligtenberg AJM, Veerman ECI (2014) Saliva: Secretion and Functions. Functions, Karger, Amsterdan. ISBN: 978-3-318-02595-8. e-ISBN: 978-3-318-02596-5.
  • Thylstrup A. and Fejerskov, O. (1994) Textbook of Clinical Cariology. 2nd ed., Munksgaard, Copenhagen. ISNB- 87-16-10916-3.