IRO Egas Moniz - Principles of Biological Chemistry

Principles of Biological Chemistry

Fundamentos de Química Biológica

Curse code:9554123

Maria Gabriela Machado De Almeida

Learning outcomes of the curricular unit:

This CU aims to provide students with a solid knowledge in fundamental areas of General Chemistry (eg solutions, molecular structure, chemical equilibrium) and Biological Chemistry, in particular (Bioanalytical, Bioorganic, Bioinorganic Chemistry). The learned subjects will be important for the study of topics taught in other CUs (eg bioenergetics, food composition, toxicology) as well as for the future professional actvities. After attending this CU, the student should be able to:

Handle laboratory material and equipment properly.
Have basic notions on chemical bonding and molecular structure.
Know the properties of aqueous solutions and measure their concentrations.
Be familiarized with the main types of chemical reactions and their equilibrium.
Know the main properties of biological molecules.
Propose separation methods of components from different types of mixtures.
Develop skills on calculations, analysis and critical reasoning.

Syllabus:

Lectures:

CHEMISTRY OF AQUEOUS SOLUTIONS.
CHEMICAL BOND
REACTIONS IN AQUEOUS SOLUTIONS
Acid-Base Equilibrium.
Oxidation-Reduction Equilibrium.
Solubility Equilibrium.
Complex formation equilibrium.
BIOORGANIC CHEMISTRY
SEPARATION TECHNIQUES

Theoretical / practical classes:

All topics related to laboratory work (safety rules) and to data treatment (errors, plotting, linear regression) will be addressed In the first theoretical-practical class (TP).
In the week following every practical class (PL), the TP class will begin with the critical analysis of the results obtained in the previous PL.
In the remaining classes as well as in all other TP, students will solve exercises related with the concepts taught in the theoretical classes (stoichiometry, preparation of aqueous solutions, chemical bonding, acid-base, solubility and redox equilibria, complex formation, organic chemistry).

Suggested Bibliography:

Chang R (1994) Química, 5th ed., McGraw-Hill, Lisboa
Jeffery GH, Bassett J, Mendham J, Denney RC (1989) Vogel's Textbook of Quantitative Chemical Analysis, 5th ed, Longman, Sci.Tech Essex
Pombeiro AJL (1991) Técnicas e Operações Unitárias em Química Laboratorial, Fundação Calouste Gulbenkian, Lisboa
Skoog D, West D & Holler F (1992) Fundamentals of Analytical Chemistry, Saunders College Publishing, 6th ed., New York

Additional Info

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